Avicenna Journal of Phytomedicine

Avicenna Journal of Phytomedicine

Antibacterial activity of Glycyrrhiza glabra against oral pathogens: an in vitro study

Document Type : Original Research Article

Authors
Fereshteh Sedighinia 1
Akbar Safipour Afshar 1
Saman soleimanpour 1
Reza zarif 2
Javad Asili 3
Kiarash Ghazvini 2
1 Department of Biology, Neyshabur Branch, Islamic Azad University, Neyshabur, I. R. Iran
2 Department of Microbiology and virology, Mashhad University of Medical Sciences, Mashhad, I. R. Iran
3 Department of Pharmacology, School of Medicine , Mashhad University of Medical Sciences , Mashhad , I.R. Iran
10.22038/ajp.2012.83
Abstract
Objectives: Oral infections and dental caries are still considered as serious public health problems and inflict a costly burden to health care services around the world and especially in developing countries.
Materials and Methods: In the present study, we evaluated the antibacterial activity of Glycyrrhiza glabra (G. glabra) against oral pathogens by diffusion methods and determined the minimum inhibitory concentration (MIC) by both broth and Agar dilution methods and minimum bactericidal concentration (MBC) by broth dilution methods.
Results: In this study, G. glabra extract showed good antibacterial activity against six bacteria. No strain in this study showed resistance against this extract.
Conclusion: G. glabrais suggested as an appropriate candidate to help us in order to control dental caries and endodontic infections.
Keywords
Antibacterial activity
Glycyrrhiza glabra
Oral Pathogen
Avicenna Journal of Phytomedicine
Volume 2, Issue 3 - Serial Number 3
May and June 2012
Pages 118-124