Document Type : Original Research Article
Department of Human Nutrition, University of Agriculture Peshawar, KP Pakistan
Department of Health and Social Sciences, University of Bedfordshire, UK
Department of Environmental Design, Health and Nutritional Sciences, Faculty of Sciences, Allama Iqbal Open University Islamabad, Pakistan
Department of Biochemistry, Khyber Medical University, Peshawar, Pakistan
Sharjah Institute for Medical Research, University of Sharjah, United Arab Emirates
Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China
Department of Biological Sciences, National University of Medical Sciences, Rawalpindi- Pakistan
Department of Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu Province, PR China
Department of Public Health, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia
Nan Shi Fu Zhong (NSFZ), Nanjing Normal University, Nanjing-China
Objective: To evaluate the effect of Ajwa dates pit powder (ADP) on lipid profile, body composition and blood pressure in patients with hyperlipidemia.
Materials and Methods: This randomized controlled clinical study was carried out on 40 patients with total cholesterol >200 mg/dl, triglycerides >150 mg/dl and BMI >25, of either sex, aged 30-50 years, who were recruited through written consent. The patients were divided into two groups (n=20 each): the ADP and the control group (CG). All patients received the doctor’s prescribed class A statin (Rosuvastatin/ Atorvastatin) 10 mg/day, while 2.7 g ADP was given on daily basis before breakfast with lukewarm water for 40 days and the control group received the same amount of wheat flour. Body composition, blood pressure and lipid profile were determined at baseline, and after 20 and 40 days. Data were analyzed by using SPSS and GraphPad Prism.
Results: ADP significantly reduced body weight (p<0.001), BMI (p<0.001), fat mass, body fat percentage, visceral fat area and waist circumference compared to the control group. Similarly, ADP significantly (p=0.000) decreased the serum level of total cholesterol and low-density lipoprotein.
Conclusion: ADP may have the potential to improve dyslipidemia and obesity.