Ethnomedicinal uses of plants for the treatment of nervous disorders at the herbal markets of Bojnord, North Khorasan Province, Iran

Document Type : Original Research Article


1 Department of Biology, Payame Noor University (PNU), Tehran, Iran

2 Department of Botany, Research Center for Plant Sciences, Ferdowsi University of Mashhad, Mashhad, Iran


Objective: Since ancient times, plants have been commonly used to cure human ailments by indigenous people throughout the world. Nervous diseases are rising all around the world. This paper provides important ethnobotanical information on plants that are used against neurological disorders and are available in medicinal markets of Bojnord, northeastern Iran.
Materials and Methods: This survey, as an ethnobotanical study, was carried out between 2017 and 2018. The identification of the intended plant species was done using the available Floras. Some important indices such as the frequency of citations, relative frequency of citation (RFC), family importance value and use report were calculated for the medicinal plants included in the present study.
Results: The present study includes 58 medicinal plant species belonging to 36 families and reports their mentioning scientific and vernacular names, parts used, and preparation method. The most common family was Lamiaceae. The major parts of the identified plants used for treatment of nervous )neuropsychological( disorders were flower and aerial parts. The most common methods used for preparation of these plants were infusion and decoction. Stachys turcomanica, Tripleurospermum disciforme, Melissa officinalis, Nardostachys jatamansi, and Aloysia citriodora had the highest rate of use report. Echium amoenum and Melissa officinalis had the highest RFC.
Conclusion: The study indicated that although people in Bojnord have access to modern medicinal preparations, a considerable number of them still use medicinal plants for therapeutic purposes. Seemingly, most cited plants are worth more precise evaluations for their pharmacological activity.


Main Subjects

Akhondzadeh S, Maleki J. 2006. Herbal medicines in the treatment of psychiatric and neurological disorders. Iran J Psychiatry, 1: 1-11.
Amiri MS, Joharachi MR. 2013. Ethnobotanical investigation of traditional medicinal plants commercialized in the markets of Mashhad. Avicina J Phytomed, 3: 254-271.
Assadi M, Maassoumi AA, Khatamsaz M, Mozaffarian V (eds.). 1988-2013. Flora of Iran. Vols. 1-77. Research institute of forests and rangelands publications. Tehran (in Persian).
Calvo MI, Cvero RY. 2015. Medicinal plants used for neurological and mental disorders in Navarra and their validation from official sources. J Ethnopharmacol, 169: 263-268.
Davidson-Hunt I. 2000. Ecological ethnobotany: sumbling toward new practices and paradigms. MASA J, 16: 1-13.
Dolatkhahi M, Dolatkhahi A, BagherNejad J. 2014. Ethnobotanical study of medicinal plants used in Arjan-Parishan protected area in Fars province of Iran. Avicinna J Phytomed, 496: 402-412.
Eslami A, khodavari H. 2016. Ethnomedicinal plants of faroujdisrrict, North Khorasan province, Iran. J Herbal Drugs, 7: 21-36.
Farhadi A, Hassanzad- Azar h, Pour-AnbariP, Joudaki Y, Shahsavari F, Bahmani M and Rafieian- kopaei M. 2016. The most important medicinal plants affecting the brain and nerves: An overview on Iranian ethnobotical sources. J Der Pharma Chemica, 8: 269-274.
Ghorbani A. 2005. Studies on pharmaceutical ethnobotant in the region of TurkmaenSahra, north of Iran (part 1): general results. J Ethnopharmacol, 102: 58-68.
Hamilton AC. 2004. Medicinal plants, conservation and livelihoods. J Biodivers. Conserv, 13: 1477-1517.
 Hussain W, Ullah M, Ghulam D astar, Badshah L. 2018. Quantitative ethnobotanical appraisal of medicinal plants used by inhabitants of lower Kurram, Kurram agency, Pakistan. Avicina J Phytomed, 8: 313-329.
Imanshahidi M, Hosseinzadeh H. 2006. The pharmacological effects of Salvia species on the central nervous system. J Phytother Res, 20: 427-437.
Iriti M, Vitalini S, Fico G, Faoro F. 2010. Neuroprotective herbs and foods from different traditional medicine and diets. J Molecules, 15: 3517-3555.
Jelodar G, Jvid Z, Sahraian A, Jelodar S. 2018. Saffron improved depression and reduced homocysteine level in patients with major depression: A Randomized, double-blind study. Avicina J Phytomed, 8: 43-50
Kantati YT, Kodjo KM, Dogbeavou KS, Vaudry D, Leprince J, Gbeassor M. 2016. Ethnopharmacological survey of plant species used in folk medicine against central nervous system disorders in Togo. J Ethnopharmacol, 181: 214-220.
Maleki T, Akhani H. 2018. Ethnobotanical and ethnomedicinal studies in Baluchi tribes: A case study in Mt. Taftan, southeastern Iran. J Ethnopharmacol, 217: 163-77.
Mosaddegh M, Naghibi F, Moazzeni H, Pirani A, Esmaeili S. 2012. Ethnobotanical survey of herbal remedies traditionally used in KohghiluyehvaBoyerAhmad province of Iran. J Ethnopharmacol, 141: 80-95
Neubauer DN. 2003. Pharmacologic approaches for the treatment of chronic insomnia. J Clin Cornerstone, 5: 16-27.
Naghibi F, Mosaddegh M, Motamed SM and Ghorbani A. 2005. Labiatae family in folk medicine in Iran: from ethnobotany to pharmacology.Iran J Pharm Res, 2:63-79
Payyappallimana U. 2010. Role of traditional medicine in primary health care: an overview of perspectives and challenges. Yokohama J SocSci, 14: 57-77.
Poorgholam P, Yaghmaei P, Hajebrahim Z. 2018. Thymoqinone recovers learning function in a rat of Alzhemer’s disease. Avicina J Phytomed, 8:188-197
Rechinger KH. 1963-2015. Flora Iranica. Vols. 1-181. Akademische Druck-u Verlagsanstalt, Graz.
Reyes-Garcia V, Luz AC, Gueze M, Paneque- Galves J, Macia MJ, Orta-Martinez M, Pino J. 2013. Secular trends on traditional ecological knowledge: an analysis of change in different domains of knowledge among Tsimane’men. J Learn Individ differ, 27: 206-212.
Sadeghi Z, Kuhestani K, Abdollahi V, Mahmood A. 2014. Ethnopharmacological studies of indigenous medicinal plants of Saravan region, Baluchistan, Iran. J Ethnopharmacol, 153: 111-118.
Sahoo S. 2018. Medicinal uses of plants for nervous disorders. Adv Complement Alt Med, 3: 1-6.
Saki K, Bahman M, Rafieian- Kopaei M, Hassanzadazar H, Dehghan K, Bahmani F, Asadzadeh J. 2014. The most common native medicinal plants used for psychiatric and neurological disorders in Urmia city, northwest of Iran. Asian Pac J Trop Dis, 4: 895-901.
Tardio J, Pardo-de Santayana M. 2008. Cultural importance indices: a comparative analysis based on the useful wild plants of southern Cantabria (northern Spain). J Eco Bot, 62: 24-39.
Thomas E, Vandebroek I, Sanca S, Van Damme P. 2009. Cultural significance of medicinal plant families and species among the Quechua farmers in Apillampampa, Bolivia. J Ethnopharmacol, 122: 60-67.
Vitalini, S, Iriti, M, Puricelli, C, Ciuchi, D, SegaleA, Fico G. 2013. Traditional knowledge on medicinal and food plants used in Val San Giacomo (Sondrio, taly) an alpine ethnobotanical study. J Ethnopharmacol, 145: 517-529.