Objective: The present study was undertaken to evaluate anti-depressant activity of Myristica fragrans(MS).
Materials and Methods: Male Wistar rats were subjected to imipramine and herbal extract ofMS for their antidepressant activity using Forced Swimming Test (FST), Reserpine Reversal Test (RRT), Haloperidol-Induced Catalepsy (HIC), and Pentobarbitone Sleeping Time (PST).
Results: Administration of MS and imipramine revealed a statistically significant reduction in immobility time in FST, RRT, and protection against HIC, compared to the control group. However, there was no significant potentiation of PST.
Conclusion: Our study demonstrated the potential antidepressant activity of MS.
Moinuddin, G., Devi, K., & Kumar Khajuria, D. (2012). Evaluation of the anti–depressant activity of Myristica fragrans (Nutmeg) in male rats. Avicenna Journal of Phytomedicine, 2(2), 72-78. doi: 10.22038/ajp.2012.33
MLA
Ghulam Moinuddin; Kshama Devi; Deepak Kumar Khajuria. "Evaluation of the anti–depressant activity of Myristica fragrans (Nutmeg) in male rats". Avicenna Journal of Phytomedicine, 2, 2, 2012, 72-78. doi: 10.22038/ajp.2012.33
HARVARD
Moinuddin, G., Devi, K., Kumar Khajuria, D. (2012). 'Evaluation of the anti–depressant activity of Myristica fragrans (Nutmeg) in male rats', Avicenna Journal of Phytomedicine, 2(2), pp. 72-78. doi: 10.22038/ajp.2012.33
VANCOUVER
Moinuddin, G., Devi, K., Kumar Khajuria, D. Evaluation of the anti–depressant activity of Myristica fragrans (Nutmeg) in male rats. Avicenna Journal of Phytomedicine, 2012; 2(2): 72-78. doi: 10.22038/ajp.2012.33
)