<?xml version="1.0" encoding="utf-8"?>
			<journal>
			<title>Avicenna Journal of Phytomedicine</title>
			<title_fa></title_fa>
			<short_title></short_title>
			<subject>Medical Sciences</subject>
			<web_url>https://ajp.mums.ac.ir/</web_url>
			<journal_hbi_system_id>0</journal_hbi_system_id>
			<journal_hbi_system_user></journal_hbi_system_user>
			<journal_id_issn>2228-7930</journal_id_issn>
			<journal_id_issn_online>2228-7949</journal_id_issn_online>
			<journal_id_pii></journal_id_pii>
			<journal_id_doi></journal_id_doi>
			<journal_id_iranmedex></journal_id_iranmedex>
			<journal_id_magiran></journal_id_magiran>
			<journal_id_sid></journal_id_sid>
			<journal_id_nlai></journal_id_nlai>
			<journal_id_science></journal_id_science>
			<language>en</language>
			<pubdate>
				<type>jalali</type>
				<year></year>
				<month></month>
				<day>1</day>
			</pubdate>
			<pubdate>
				<type>gregorian</type>
				<year></year>
				<month></month>
				<day>1</day>
			</pubdate>
			<volume></volume>
			<number></number>
			<publish_type>online</publish_type>
			<publish_edition>1</publish_edition>
			<article_type>fulltext</article_type>
			<articleset><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Biological potential of nano-curcumins in dental and maxillofacial infections and inflammation: A systematic review</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>Review Article</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Objective: Periodontitis is a prevalent oral infection with increasing global incidence. This study investigated the biological potential and therapeutic benefits of nano-curcumins (Nano-CURs) for preventing and managing dental and maxillofacial infections and their associated inflammatory complications.Materials and methods: This systematic review followed PRISMA guidelines and included preclinical and clinical studies retrieved from PubMed/MEDLINE, Web of Science, Scopus, Embase, and the Cochrane Library before August 18, 2025.Results: In 23 included studies, Nano-CURs mainly comprised periodontitis, gingivitis, ligature-induced periodontitis, lipopolysaccharide-induced periodontal disease, and peri-implantitis. CUR-based nanocarriers improve solubility, bioavailability, and the controlled release of the drug. These nanocarriers demonstrate potent antibacterial and antibiofilm activity against key periodontal and peri-implant pathogens. It also attenuates inflammatory signaling, decreases cytokine production and oxidative stress, and possesses favorable biocompatibility.Conclusion: Evidence derived predominantly from preclinical studies indicates that Nano-CURs are well tolerated and may effectively inhibit dental and maxillofacial infections and associated inflammation.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>Curcumin Nanoparticles Anti, inflammatory agents Periodontitis Dental caries Periodontal Diseases</keyword>
				<start_page>0</start_page>
				<end_page>0</end_page>
				<web_url>https://ajp.mums.ac.ir/article_27943.html</web_url>
			<author_list><author>
				<first_name>Reza</first_name>
				<middle_name></middle_name>
				<last_name>Fallah Tafti</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>rezafallah1372.rft@gmail.com</email>
				<code>122856</code>
				<coreauthor>No</coreauthor>
				<affiliation>1. Research Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran.
2.  Department of Endodontics, School of Dentistry, Baqiyatallah University of Medical Sciences, Tehran, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Saber</first_name>
				<middle_name></middle_name>
				<last_name>Abbaszadeh</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>saberabaszade1370@gmail.com</email>
				<code>122857</code>
				<coreauthor>No</coreauthor>
				<affiliation>Medical Student, Student Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran. E-mail: saberabaszade1370@gmail.com</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Uliana</first_name>
				<middle_name></middle_name>
				<last_name>Y. Chugaeva</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>chugaeva_sechenov@inbox.ru</email>
				<code>122858</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Pediatric, Preventive Dentistry and Orthodontics, Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia. E-mail: chugaeva_sechenov@inbox.ru, ORCID: 0000-0003-2854-9559</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Mohadeseh</first_name>
				<middle_name></middle_name>
				<last_name>Karimian</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>mohadesehkarimian18@gmail.com</email>
				<code>122859</code>
				<coreauthor>No</coreauthor>
				<affiliation>Student Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran. E-mail: mohadesehkarimian18@gmail.com. ORCID: 0000-0002-8462-9118.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Saeid</first_name>
				<middle_name></middle_name>
				<last_name>Heidari-Soureshjani</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>heidari_62@yahoo.com</email>
				<code>122860</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Shahrekord University of Medical Sciences</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Catherine</first_name>
				<middle_name>MT</middle_name>
				<last_name>Sherwin</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>catherine.sherwin@wright.edu</email>
				<code>122861</code>
				<coreauthor>No</coreauthor>
				<affiliation>Professor and Vice-Chair for Research, Pediatric Clinical Pharmacology and Toxicology, Department of Pediatrics, Wright State University Boonshoft School of Medicine, Dayton Children&amp;#039;s Hospital, One Children&amp;#039;s Plaza, Dayton, Ohio, USA.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article>
			</articleset>
			</journal>