<?xml version="1.0" encoding="utf-8"?>
			<journal>
			<title>Avicenna Journal of Phytomedicine</title>
			<title_fa></title_fa>
			<short_title></short_title>
			<subject>Medical Sciences</subject>
			<web_url>https://ajp.mums.ac.ir/</web_url>
			<journal_hbi_system_id>0</journal_hbi_system_id>
			<journal_hbi_system_user></journal_hbi_system_user>
			<journal_id_issn>2228-7930</journal_id_issn>
			<journal_id_issn_online>2228-7949</journal_id_issn_online>
			<journal_id_pii></journal_id_pii>
			<journal_id_doi></journal_id_doi>
			<journal_id_iranmedex></journal_id_iranmedex>
			<journal_id_magiran></journal_id_magiran>
			<journal_id_sid></journal_id_sid>
			<journal_id_nlai></journal_id_nlai>
			<journal_id_science></journal_id_science>
			<language>en</language>
			<pubdate>
				<type>jalali</type>
				<year>0</year>
				<month>0</month>
				<day>1</day>
			</pubdate>
			<pubdate>
				<type>gregorian</type>
				<year>2011</year>
				<month>9</month>
				<day>1</day>
			</pubdate>
			<volume>1</volume>
			<number>2</number>
			<publish_type>online</publish_type>
			<publish_edition>1</publish_edition>
			<article_type>fulltext</article_type>
			<articleset><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Antidepressant-like effect of aqueous extract from Rosa damascena in mice</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>Original Research Article</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Objective: Rosa damascena mill L (R. damascena) is an ornamental plant that has several therapeutic (such as sedative and hypnotic) effects. It also heals depression, grief, nervous stress and tension. In the present study we evaluated antidepressant-like effect of R. damascena using forced swimming test (FST).
Material and Methods: Three doses of aqueous extract (15, 60 and 90 mg/kg) was injected intraperitoneally. After 30 min of injection, immobility and swimming times were measured and compared with control (negative control) and imipramine (positive control).
Results: The results showed that low dose (15mg/kg) of extract significantly increased swimming time and decreased immobility time. However, the two high doses of extract (60 and 90mg/kg) had no significant effect on these parameters.
 Conclusion: These results proposed antidepressant-like effect of low concentration of aqueous extract of R. damascena.
 ]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>Rosa damascena, Mice, Immobility time, Antidepressant-like effect</keyword>
				<start_page>91</start_page>
				<end_page>97</end_page>
				<web_url>https://ajp.mums.ac.ir/article_127.html</web_url>
			<author_list><author>
				<first_name>Karim</first_name>
				<middle_name></middle_name>
				<last_name>Dolati</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email></email>
				<code>429</code>
				<coreauthor>No</coreauthor>
				<affiliation>Pharmacological Research Center of Medicinal Plants and Department of Pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I. R. Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Hassan</first_name>
				<middle_name></middle_name>
				<last_name>Rakhshandeh</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email></email>
				<code>430</code>
				<coreauthor>No</coreauthor>
				<affiliation>Pharmacological Research Center of Medicinal Plants and Department of Pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I. R. Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Mohammad Naser</first_name>
				<middle_name></middle_name>
				<last_name>Shafei</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>shafeimn@mums.ac.ir</email>
				<code>431</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Neuroscience Research Center and Department of Physiology, School of medicine, Mashhad
University of Medical Sciences, Mashhad, I. R. Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article>
			</articleset>
			</journal>