TY - JOUR ID - 15067 TI - Evaluation of the influence of chamomile vaginal gel on dyspareunia and sexual satisfaction in postmenopausal women: A randomized, double-blind, controlled clinical trial JO - Avicenna Journal of Phytomedicine JA - AJP LA - en SN - 2228-7930 AU - Bosak, Zahra AU - Iravani, Mina AU - Moghimipour, Eskandar AU - Haghighi zadeh, Mohammad Hossein AU - Jelodarian, Parivash AU - Khazdair, Mohammad Reza AD - Student Research Committee, School of Nursing and Midwifery, Menopause Andropause Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AD - Department of Midwifery, Menopause Andropause Research Center, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AD - Department of Pharmaceutics, School of Pharmacy, Medicinal Plant Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AD - Department of Biostatistics, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AD - Department of Obstetrics and Gynecology, Fertility Infertility and Perinatology Research Center, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AD - Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran Y1 - 2020 PY - 2020 VL - 10 IS - 5 SP - 481 EP - 491 KW - Sexual satisfaction KW - chamomile vaginal gel KW - painful intercourse KW - Menopause DO - 10.22038/ajp.2020.15067 N2 - Objective: The purpose of this study was to determine the effect of chamomile vaginal gel on dyspareunia and sexual satisfaction in postmenopausal women. The phytoestrogenic properties of Matricaria chamomilla were the reason for selection of this plant. Materials and Methods: This double-blind clinical trial research was conducted on 96 eligible postmenopausal women referring to Gotvand city Health Center No. 1 in 2018. In this research, 96 postmenopausal women complaining from dyspareunia and sexual dissatisfaction were randomly assigned into three groups (each contained 32 subjects) to receive 5% chamomile vaginal gel, conjugated estrogen vaginal cream and placebo gel, for 12 weeks. All women completed the Larsson and a four-degree pain self-assessment questionnaires. Data was analyzed using SPSS version 22. A p-value of less than 0.05 was considered significant. Results: After the intervention period, a significant difference was seen between the intervention and the placebo group in the mean sexual satisfaction (p<0.001). Also, a significant reduction was seen in painful sexual intercourse between the groups using vaginal gel of chamomile and conjugated estrogen vaginal cream (95% CI: chamomile: 0.68-1.04, estrogen: 0.63-0.98, placebo: 1.8-2.1; p<0.001).  Conclusion: Using chamomile vaginal gel can cause a reduction in painful sexual intercourse and an increase in sexual satisfaction in postmenopausal women. UR - https://ajp.mums.ac.ir/article_15067.html L1 - https://ajp.mums.ac.ir/article_15067_e4b2bb12ddee097f437f3e937f589ed8.pdf ER -