@article { author = {Doosti, Fatemeh and Dashti, Saeedeh and Tabatabai, Seyed Meghdad and Hosseinzadeh, Hossein}, title = {Traditional Chinese and Indian medicine in the treatment of opioid-dependence: a review}, journal = {Avicenna Journal of Phytomedicine}, volume = {3}, number = {3}, pages = {205-215}, year = {2013}, publisher = {Mashhad University of Medical Sciences}, issn = {2228-7930}, eissn = {2228-7949}, doi = {10.22038/ajp.2013.514}, abstract = {Objective: In this study, the current literatures on the use of herbs and herbal preparations of Traditional Chinese and Indian Medicine for the treatment of opioid addiction were reviewed. Methods: Search was done in databases such as Pub Med, Science Direct, Scopus, Springer Link, and Google Scholar. Results: Among 18 retrieved studies, 3 studies were about asafetida extract, an approved preparation for ameliorating drug abstinence in China. Chinese preparations including Composite Dong Yuan Gao, Qingjunyin and TJ-97 (a water extract of dai-bofu-to) as well as Indian ones, Mentate and Shilajit, were reported to have positive effects against opioid withdrawal, dependence, and tolerance. Moreover, Levo-tetrahydropalmatine and L-Stepholidine, in addition to extracts of Caulis Sinomenii and Sinomenium acutum showed similar effects. Banxia Houpu Decoction, Fu-Yuan pellet, Jinniu capsules, Qingjunyin, Tai-Kang-Ning capsule, and Xuan Xia Qudu Jiaonang (WeiniCom) from Chinese preparations, showed anti-addiction effects in randomized, double-blind and, in some studies, multicenter clinical trials. Conclusion: Traditional herbal preparations of China and India have anti-addiction effects with less adverse effects than alpha2-adrenergic or opioid agonists.}, keywords = {Addiction,Opioid Tolerance,Opioid withdrawal,Traditional Chinese Medicine,Traditional Indian Medicine}, url = {https://ajp.mums.ac.ir/article_514.html}, eprint = {https://ajp.mums.ac.ir/article_514_e5e4d96be6607f5071f17d0a91f50c73.pdf} }