Effect of virgin olive oil versus piroxicam phonophoresis on exercise-induced anterior knee pain

Document Type : Original Research Article

Authors

1 Department of Exercise Physiology, Islamic Azad University-Ardabil Branch, Ardabil, Iran

2 Department of Exercise Physiology, University of Mohaghegh- Ardabili, Ardabil, Iran

3 Department of Pharmacology, School of Pharmacy, Ardabil University of Medical Sciences, Ardabil, Iran

Abstract


Objective: The main purpose of this study was to evaluate the effects of virgin olive oil phonophoresis on female athletes' anterior knee pain (AKP).
Materials and Methods: A double blinded randomized clinical trial was conducted. Ninety-three female athletes suffering from AKP voluntarily participated in this study. Patients were randomly assigned into olive oil (n=31), piroxicam (n=31) or base gel phonophoresis (n=31) groups. At the baseline visit, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire was filled by subjects who were then treated with olive oil, piroxicam or pure phonophoresis for 12 sessions. After 6 and 12 sessions of physiotherapy, subjects filled the questionnaire again. Main outcomes were significant improvement in pain, stiffness, physical function, and total WOMAC scores.
Results: Although, there was a significant reduction in symptoms of AKP at the end of the therapy in all groups (p< 0.05), but in olive oil group, this improvement was seen after 6 sessions of treatment (p< 0.001). A significant difference between olive oil group and piroxicam and/or phonophoresis group was observed after 6 sessions of therapy (p< 0.05).
Conclusion: It could be proposed that phonophoresis with virgin olive oil is as effective as piroxicam gel on lowering WOMAC scores of AKP in female athletes and also has several beneficial properties including faster effect and shorter duration of therapy. The exact mechanism of beneficial action of virgin olive oil on AKP is not clear and requires further studies.

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Adams W. 2004. Treatment Options in Overuse Injuries of the Knee: Patellofemoral Syndrome, Iliotibial Band Syndrome, and Degenerative Meniscal Tears. pp. 256-260, American College of Sports Medicine.
Beauchamp GK, Keast RS, Morel D, Lin J, Pika J, Han Q, Lee CH, Smith AB, Breslin PA. 2005. Phytochemistry: ibuprofen-like activity in extra-virgin olive oil. Nature, 437: 45-46.
Bohlooli S, Jastan M, Nakhostin-Roohi B, Mohammadi S, Baghaei Z. 2012. A pilot double-blinded, randomized, clinical trial of topical virgin olive oil versus piroxicam gel in osteoarthritis of the knee. J Clin Rheumatol, 18: 99-101.
Bolin D, Md P. 2003. Transdermal Approaches to Pain in Sports Injury Management. pp. 303-309, American College of Sports Medicine.
Byl NN. 1995. The use of ultrasound as an enhancer for transcutaneous drug delivery: phonophoresis. Phys Ther, 75: 539-553.
Ciccone CD, Leggin BG, Callamaro JJ. 1991. Effects of ultrasound and trolamine salicylate phonophoresis on delayed-onset muscle soreness. Phys Ther, 71: 666-675.
Davis JWL, Fulkerson JP. 1999. Initial evaluation of the athletewith anterior knee pain. Oper Tech Sports Med, 7: 55-58.
DeLisa JA. 1988. Rehabilitation medicine : principles and practice. pp. 251-270, Lippincott, Philadelphia.
Garrido M, Gonzalez-Flores D, Marchena AM, Prior E, Garcia-Parra J, Barriga C, et al. 2013. A lycopene-enriched virgin olive oil enhances antioxidant status in humans. J Sci Food Agric, 93: 1820-1826.
Griffin JE, Touchstone JC. 1968. Low-intensity phonophoresis of cortisol in swine. Phys Ther, 48: 1336-1344.
Kleinkort JA, Wood F. 1975. Phonophoresis with 1 percent versus 10 percent hydrocortisone. Phys Ther, 55: 1320-1324.
Kremer JM, Lawrence DA, Jubiz W, DiGiacomo R, Rynes R, Bartholomew LE, et al. 1990. Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects. Arthritis Rheum, 33: 810-820.
Llopis E, Padrón M. 2007. Anterior knee pain. Eur J Radiol, 62: 27-43.
Martinez-Beamonte R, Navarro MA, Acin S, Guillen N, Barranquero C, Arnal C, et al. 2013. Postprandial changes in high density lipoproteins in rats subjected to gavage administration of virgin olive oil. PLoS One, 8: e55231.
Menendez JA, Joven J, Aragones G, Barrajon-Catalan E, Beltran-Debon R, Borras-Linares I, et al. 2013. Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents. Cell Cycle, 12: 555-578.
Michlovitz SL. 1990. Thermal agents in rehabilitation. pp. 152-155, Davis, Philadelphia.
Musumeci G, Trovato FM, Pichler K, Weinberg AM, Loreto C, Castrogiovanni P. 2013. Extra-virgin olive oil diet and mild physical activity prevent cartilage degeneration in an osteoarthritis model: an in vivo and in vitro study on lubricin expression. J Nutr Biochem, 24: 2064-2075.
Nakhostin- Roohi B, Bohlooli S. 2014. Comparison the Efficacy of Ultrasound Therapy and Phonophoresis with Virgin Olive Oil on Athletes' Chronic Low Back Pain: A Pilot Study. J Zanjan Univ Med Sci , 22: 43-51.
Nimon G, Murray D, Sandow M, Goodfellow J. 1998. Natural History of Anterior Knee Pain: A 14- to 20-Year Follow-up of Nonoperative Management.
Owen RW, Giacosa A, Hull WE, Haubner R, Wurtele G, Spiegelhalder B, et al. 2000. Olive-oil consumption and health: the possible role of antioxidants. Lancet Oncol, 1: 107-112.
Oziomek RS, Perrin DH, Herold DA, Denegar CR. 1991. Effect of phonophoresis on serum salicylate levels. Med Sci Sports Exerc, 23: 397-401.
Perona JS, Cabello-Moruno R, Ruiz-Gutierrez V. 2006. The role of virgin olive oil components in the modulation of endothelial function. J Nutr Biochem, 17: 429-445.
Sanchez-Fidalgo S, Cardeno A, Sanchez-Hidalgo M, Aparicio-Soto M, de la Lastra CA. 2013. Dietary extra virgin olive oil polyphenols supplementation modulates DSS-induced chronic colitis in mice. J Nutr Biochem. 24:1401-13.
Stark AH, Madar Z. 2002. Olive oil as a functional food: epidemiology and nutritional approaches. Nutr Rev, 60: 170-176.
Stracciolini A, Meehan Iii WP, d'Hemecourt PA. 2007. Sports Rehabilitation of the Injured Athlete. Clin Pediatr Emerg Med, 8: 43-53.
Taunton JE, Wilkinson M. 2001. Rheumatology: 14. Diagnosis and management of anterior knee pain. Can Med Assoc J , 164: 1595-1601.
Vazquez-Martin A, Fernandez-Arroyo S, Cufi S, Oliveras-Ferraros C, Lozano-Sanchez J, Vellon L, Micol V, Joven J, Segura-Carretero A, Menendez JA. 2012. Phenolic secoiridoids in extra virgin olive oil impede fibrogenic and oncogenic epithelial-to-mesenchymal transition: extra virgin olive oil as a source of novel antiaging phytochemicals. Rejuvenation Res, 15: 3-21.
Waterman E, Lockwood B. 2007. Active components and clinical applications of olive oil. Altern Med Rev, 12: 331-342.