TY - JOUR ID - 514 TI - Traditional Chinese and Indian medicine in the treatment of opioid-dependence: a review JO - Avicenna Journal of Phytomedicine JA - AJP LA - en SN - 2228-7930 AU - Doosti, Fatemeh AU - Dashti, Saeedeh AU - Tabatabai, Seyed Meghdad AU - Hosseinzadeh, Hossein AD - School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, I. R. Iran AD - Pharmaceutical Research Center, Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, I. R. Iran Y1 - 2013 PY - 2013 VL - 3 IS - 3 SP - 205 EP - 215 KW - Addiction KW - Opioid Tolerance KW - Opioid withdrawal KW - Traditional Chinese Medicine KW - Traditional Indian Medicine DO - 10.22038/ajp.2013.514 N2 - Objective: In this study, the current literatures on the use of herbs and herbal preparations of Traditional Chinese and Indian Medicine for the treatment of opioid addiction were reviewed. Methods: Search was done in databases such as Pub Med, Science Direct, Scopus, Springer Link, and Google Scholar. Results: Among 18 retrieved studies, 3 studies were about asafetida extract, an approved preparation for ameliorating drug abstinence in China. Chinese preparations including Composite Dong Yuan Gao, Qingjunyin and TJ-97 (a water extract of dai-bofu-to) as well as Indian ones, Mentate and Shilajit, were reported to have positive effects against opioid withdrawal, dependence, and tolerance. Moreover, Levo-tetrahydropalmatine and L-Stepholidine, in addition to extracts of Caulis Sinomenii and Sinomenium acutum showed similar effects. Banxia Houpu Decoction, Fu-Yuan pellet, Jinniu capsules, Qingjunyin, Tai-Kang-Ning capsule, and Xuan Xia Qudu Jiaonang (WeiniCom) from Chinese preparations, showed anti-addiction effects in randomized, double-blind and, in some studies, multicenter clinical trials. Conclusion: Traditional herbal preparations of China and India have anti-addiction effects with less adverse effects than alpha2-adrenergic or opioid agonists. UR - https://ajp.mums.ac.ir/article_514.html L1 - https://ajp.mums.ac.ir/article_514_e5e4d96be6607f5071f17d0a91f50c73.pdf ER -