TY - JOUR ID - 2161 TI - Otostegia persica (Lamiaceae): A review on its ethnopharmacology, phytochemistry, and pharmacology JO - Avicenna Journal of Phytomedicine JA - AJP LA - en SN - 2228-7930 AU - Sadeghi, Zahra AU - Akaberi, Maryam AU - Valizadeh, Jafar AD - Agricultural Research Center, High Educational complex of Saravan, I. R. Iran AD - Biotechnology Research Center and School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, I. R. Iran AD - Department of Biology, University of Sistan & Baluchestan, Zahedan, I. R. Iran Y1 - 2014 PY - 2014 VL - 4 IS - 2 SP - 79 EP - 88 KW - Otostegia KW - Pharmacology KW - Phytochemistry KW - Toxicity KW - Therapeutics KW - Traditional Medicine DO - 10.22038/ajp.2014.2161 N2 - Abstract Objective: The current study summarizes the updated information concerning the ethnopharmacology, Phytochemistry, and pharmacology of Otostegia persica Boiss. (Lamiaceae), an endemic medicinal plant in south and southeast of Iran. Materials and Methods: Information was collected through bibliographic investigation from scientific journals, books, theses, reports, and electronic search (databases SCOPUS, Google Scholar, Web of Science, and Science Direct). Moreover, documentation from unpublished resources and ethnobotanical surveys has been used. The present review covers the literature available from 2003 to 2013. Results: In traditional systems of medicine, this plant is reputed for treating diabetes, arthritis, gastric discomfort, headache, rheumatism, sedative activities, regulating blood pressure, and hyperlipidemia. Phytochemical screening of active components and mineral element evaluation of this species have been reported. Several types of diterpenoids and flavonols including morin, kaempferol, and quercetin are identified from the plant. Most of the pharmacological activity of this plant resides in its flavonoid fraction which causes antimicrobial and antioxidant activities. Various pharmacological studies on O. persica show antimicrobial, antioxidant, anti-inflammatory, anti-diabetic, anti-aphid, and hepatoprotective activities. Conclusion: Being an endemic plant of Iran, this species is an important medicinal herb which can be used for various purposes. This review might be helpful for scientists and researchers to find new chemical entities responsible for its claimed traditional uses and discover new lead compounds for diseases mentioned. UR - https://ajp.mums.ac.ir/article_2161.html L1 - https://ajp.mums.ac.ir/article_2161_9e5779fd4a4ab6f8eb80501572f77ac9.pdf ER -