@article { author = {Bhatia, Saurabh and Sharma, Kiran and Sharma, Ajay and Nagpal, Kalpana and Bers, Tanmoy}, title = {Anti-inflammatory, Analgesic and Antiulcer properties of Porphyra vietnamensis}, journal = {Avicenna Journal of Phytomedicine}, volume = {5}, number = {1}, pages = {69-77}, year = {2015}, publisher = {Mashhad University of Medical Sciences}, issn = {2228-7930}, eissn = {2228-7949}, doi = {10.22038/ajp.2014.3758}, abstract = {Objectives: Aim of the present work was to investigate the anti-inflammatory, analgesic and antiulcer effects of red seaweed Porphyra vietnamensis (P. vietnamenis). Materials and Methods: Aqueous (POR) and alcoholic (PE) fractions were successfully isolated from P. vietnamenis. Further biological investigations were performed using a classic test of paw edema induced by carrageenan, writhing induced by acetic acid, hot plate method and naproxen induced gastro-duodenal ulcer. Results: Among the fractions POR showed better activity.  POR and PE significantly (p < 0.05) reduced carrageenan induced paw edema in a dose dependent manner. In the writhing test POR significantly (p < 0.05) reduced abdominal writhes than PE.  In hot plate method POR showed better analgesic activity than PE. POR showed comparable ulcers reducing potential (p<0.01) to that of omeprazole, and has more ulcer reducing potential then PE. Conclusions: The results of this study demonstrated that P. vietnamenis aqueous fraction possesses biological activity that is close to the standards taken for the treatment of peripheral painful or/and inflammatory and ulcer conditions.}, keywords = {Porphyra,Porphyran,Carrageenan,Analgesia,Ulcer}, url = {https://ajp.mums.ac.ir/article_3758.html}, eprint = {https://ajp.mums.ac.ir/article_3758_5dd45b899ba3d030482a8d526d7371a2.pdf} }