p. 96−113
2228-7949
Vol.8/No.2
0.05). Conclusion: Methanolic extracts of N. sativa showed therapeutic effects against H. columbae and may be regarded as a suitable choice for further studies to develop new drugs against blood parasites, in both animals and human beings.]]>
p. 114−121
2228-7949
Vol.8/No.2
100 µg/ml. In the acute study in mice, intra-peritoneal administration caused dose-dependent adverse effects and mortality with an LD50 of 4.06 ± 0.01 g/kg.In the chronic tests, neither mortality nor visible signs of lethality was seen in rats. Even AST and ALT were not affected while a significant decrease in serum glucose levels, at 300 and 600 mg/kg was detected. Histopathological examination of the kidney and liver did not show any alteration or inflammation at the end of treatment. Conclusion: In conclusion, the aqueous extract of C. villosa seed appeared to be non-toxic and did not produce mortality or clinically significant changes in the haematological and biochemical parameters in rats.]]>
p. 122−135
2228-7949
Vol.8/No.2
p. 136−142
2228-7949
Vol.8/No.2
p. 143−151
2228-7949
Vol.8/No.2
p. 152−160
2228-7949
Vol.8/No.2
p. 161−169
2228-7949
Vol.8/No.2
0.05), and creatinine (p<0.05), as well as urine pH (p<0.05) decreased in groups C and D, compared to group B. Also, urine calcium level, urine uric acid (p>0.05), and urine volume (p<0.05) were higher in group D, compared to group B. In addition, the serum level of calcium, creatinine (p<0.05), and uric acid (p<0.001) decreased in groups C and D. Conclusion: The aqueous extract of chicory flower (50 mg/kg) could reduce the number of calcium oxalate deposits in the urine and reduce the level of serum parameters.]]>
p. 170−178
2228-7949
Vol.8/No.2
p. 179−187
2228-7949
Vol.8/No.2